Subtract You by Zebrahead is about the challenging end of a tumultuous relationship. The lyrics explore themes of heartbreak, resentment, and the struggle to move on. The singer expresses frustration and sadness over the breakup, highlighting how difficult it is to 'subtract' the person from their life. Poignant moments include reflections on the wasted time and effort put into the relationship, and the realization that moving forward requires letting go, even though it's painful.