Nothing Really Matters by Will.I.Am is a reflection on the importance of love and connection over material wealth and external success. The song emphasizes that true fulfillment comes from meaningful relationships rather than the accumulation of physical possessions. Key themes include love, connection, and the superficial nature of materialism. Poignant moments in the song are where Will.I.Am stresses that all the riches in the world can't compare to the feeling of genuine love and togetherness.