Do Yourself a Favor by Stevie Wonder encapsulates a powerful message about self-empowerment and the importance of making decisions that are true to one's own interests rather than succumbing to external pressures or negativity. The song urges listeners to take control of their own lives, avoid toxic influences, and find strength within themselves to pursue happiness and fulfillment. Key themes in this song include self-respect, resilience, and positive self-affirmation. Poignant moments arise when the lyrics emphasize the need to move away from harmful situations and people who do not wish well, reinforcing the idea that personal happiness and well-being should be a priority.