Christian Brothers by Elliott Smith explores themes of addiction, self-destruction, and the yearning for escape. The song's narrative addresses the struggles with substance abuse and the cyclical nature of dependence. The protagonist's internal conflict is evident as they grapple with their vices and the impact it has on their relationships. Poignant moments in the song include lines that reveal deep self-awareness and a cry for help, highlighting the emotional turmoil and sense of entrapment felt by the speaker.