Isn't It Strange by Don McLean is a poignant song that captures the fleeting and often puzzling nature of life and relationships. The lyrics inquire into the complexities and contradictions that people experience when they fall in and out of love. McLean reflects on the beauty and melancholy that coexist in life, evoking a sense of introspection and nostalgia. Key themes include love, loss, and the passage of time. Moments that stand out in the song include the singer's contemplative questions about the oddities and heartaches that people face, highlighting how emotions can be both deeply profound and inexplicably strange.