Only Game In Town by America explores themes of loneliness, desire, and solace found in a relationship that seems to be filling a void rather than being built on genuine love. The song describes a sense of isolation and yearning for connection, suggesting that the relationship is more about escaping loneliness than true affection. Notable poignant moments include the lyrics that underscore the sense of desperation and resignation, painting a picture of a person feeling that their current relationship is the only option they have.