Alicia Keys' song 'Tell You Something (Nana's Reprise)' is a soulful ballad that delves into the theme of life's fleeting moments and the importance of expressing love and appreciation before it's too late. Inspired by the passing of her grandmother (Nana), Keys emphasizes the need to communicate heartfelt emotions to loved ones. The poignant moments in the song arise when Keys reflects on regret and the realization that life is unpredictable, urging listeners to cherish every moment and to never hold back from telling someone you love them. The song blends vulnerability and raw emotion, making it a touching tribute to her grandmother and a universal reminder about the brevity of life.